In reality, small chemical compounds of 700-1500 Da are not appropriate immunogens. But, when attached to macromolecules, they usually become great immunogenic agents. These small molecules are referred to as a hapten and macromolecules conferring hapten immunogenic are referred to as a carrier. The hapten can be thought of as an exogenous epitope linked to the carrier.
Learn more: Tetracyclines Hapten Design
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