Cataliesw

Creative Biolabs provides a comprehensive range of customized, high-quality services in single cell nuclei RNA sequencing service to support scientific research in related biomedical industries worldwide, as well as a single-cell level research application platform for complex tissues such as brain tissue, heart, kidney, or some rare cryopreserved samples, making it easier to explore tumor cell heterogeneity and pathogenic mechanisms. Check more details: Single Nuclei RNA Sequencing Service

The novel coronavirus, named SARS-CoV-2, is now rapidly spreading across the world after originating in the city of Wuhan, China. Human-to-human transmission of this virus has been identified in familial case cluster reports, and additional cases continue to be confirmed in different cities and countries around the world.

CAR-T cell therapy has made great achievements in the past decade, while conventional CAR-T cell therapy also has some obstacles to overcome, such as the CRS and ICANS toxicity, and the expensive and complex manufacturing process. The in-vivo CAR-T cell engineering by nanoparticles carrying CAR genes and gene-editing tools has shown potential breakthroughs in overcoming the above obstacles of traditional CAR-T cell therapies. Therefore, there is more urgent to develop safe and simple in-vivo CAR-T cell engineering solutions.

Creative Biolabs is one of the well-recognized expert professionals in the field of complement therapeutics and related services. Our technical experts are looking forward to offering high-quality and custom complement inhibitor validation services for our clients.

As a leading company in the antibody development market, experts in Creative Biolabs possess enriched experience in bispecific antibody (BsAb) development. We can offer many different technical platforms and BsAb formats for customers and focus on ideal BsAbs design and development that meet all requirements of the customers.

To investigate the possible toxicity of novel drug candidates before they are introduced to the human body, safety evaluation is a crucial component of preclinical research. Our toxicity research division at Creative Biolabs is staffed by interdisciplinary experts and conveniently located preclinical facilities worldwide, guaranteeing that the possible toxicity of your medication is accurately described. You can always rely on our team's extensive preclinical drug development knowledge to provide you with trustworthy safety assessment findings.

A unique class of antibody known as BsAb is capable of reacting with two distinct targets at once, such as cells, ligands, receptors, antigens, and epitopes. Bispecific single-domain antibodies, bispecific diabodies, bispecific Fab domains, and so on are examples of the various structures and formats that can be created for BsAbs (see Fig. 1). These structures and formats are generally classified into two classes: IgG-like (structures that contain an Fc region) and non-IgG-like (structures lacking an Fc region). Since these broad-spectrum BsAbs bind to both a target and a cytotoxic cell at the same time, they are highly effective for cancer immunotherapy and are widely used for diagnosis, prophylaxis, drug delivery, and therapy.

Exosomes are distinguished by their distinct internal contents and membrane proteins. The identification of particular exosomal markers, such as internal protein TSG101 and membrane proteins CD63, CD9, and CD81, allows for the quantification of exosome purity and the confirmation of exosome presence in samples. Furthermore, distinct marker proteins may be expressed by exosomes secreted by various cell types. By identifying these specific markers, researchers can differentiate and identify exosomes originating from diverse cellular sources.

An acknowledged authority in the field of producing and generating antibodies is Creative Biolabs. In particular, we have started offering a range of in vitro diagnostic (IVD) antibody development services for various illnesses and infections. Novel disease biomarkers have been discovered as a result of scientific advancement, meeting the demand for a quicker, more precise, and more accurate diagnosis. Specifically, we offer IVD antibody development services for the marker troponin.

To satisfy the demands and expectations of clients purchasing clinical materials, Creative Biolabs is building cutting-edge facilities and technologies to produce AAV, lentivirus, and adenovirus under strict GMP quality control. To guarantee end-to-end quality compliance, we have assembled a robust process development and GMP team comprising virologists and technologists, a skilled quality control (QC) professional, and a GMP research team. Our flexible and superior GMP virus packaging services cover everything from construction design to the production, concentration, and titration of lentiviral vectors.

Neuroscience, also known as neurobiology, is the scientific study of the structure and function of the nervous system. Combined with multiple disciplines, it focuses on the study of the nervous system with different approaches and different scales. Neural tissue damage in the peripheral nervous system (PNS) and central nervous system (CNS) may result in multiple neurological diseases and even life-long disabilities. Neural tissue engineering is a promising strategy for neural repair and neurological diseases treatment. In this case, proper preclinical models are required to mimic the micro-environment. Here, Creative Biolabs has developed the STEMOD™ neuroscience ex vivo models for our clients all over the world.

This product is a Complement Serum freshly prepared from Human whole blood in cold and then frozen at -80°C to prevent degradation of complement activity. It can be used in the hemolytic plaque assays, complement fixation assays, and other lymphocytotoxicity and hemolytic procedures. This product is for research use only and is not intended for therapeutic or diagnostic applications.